Background. Cerebral injury remains a significant complication of card
iac operations. We determined the incidence of cerebral dysfunction in
a population of elderly patients undergoing open chamber cardiac oper
ations (group 1) as compared with a younger population (group 2) and a
n age-matched group of elderly patients undergoing major noncardiac op
erations (group 3). Methods. Sixty-eight patients (55 for open chamber
cardiac operations and 13 for noncardiac operations) were prospective
ly studied. Patients were evaluated preoperatively and postoperatively
before hospital discharge using a complete neurologic examination and
a battery of standard neuropsychometric tests, and at surgical follow
-up with neuropsychometric tests only. Results. Postoperative changes
detected by neurologic examination consisted of the appearance of new
primitive reflexes in all groups. No statistically significant differe
nces in incidence were found. The neuropsychometric performance of gro
up 1 patients was statistically different from that of patients in gro
ups 2 and 3 only in the early follow-up period. Conclusions. Elderly p
atients having open chamber cardiac operations exhibit significantly m
ore cerebral dysfunction in the early postoperative period than those
undergoing major noncardiac operations and younger patients after open
chamber procedures. These changes do not persist into the late follow
-up period.