Calculations are reported of the molecular abundances in a cloud subje
cted to varying ionizing fluxes and attention is drawn to the molecule
s which survive as the intensity is increased. The calculations suppor
t the suggestion of Phillips & Lazio (1995) that the absence of HCO+ n
ear the hard X-ray source 1E1740.7-2942 may be due to a high X-ray flu
x. The calculations also raise the possibility that the anomalous HCN/
CO ratio observed in the Seyfert Galaxy NGC 1068 may be a consequence
of X-ray ionization. High abundances are predicted for CN and NO. Obse
rvations of these may serve to distinguish between the different scena
rios.