NEPHROTIC SYNDROME IN A MOTHER AND HER INFANT - RELATIONSHIP WITH CYTOMEGALOVIRUS-INFECTION

This case report describes infantile nephrotic syndrome (NS) in a baby girl with a clinically severe cytomegalovirus (CMV) infection. Cultur e of the baby's urine was positive for CMV and IgM anti-CMV antibodies were detected. After an unsuccessful course of corticosteroids, gancy clovir treatment was started and a remission of cutaneous, pulmonary, and renal symptoms was achieved. As the mother also developed NS at th e end of pregnancy, a common etiology could be postulated, although th ere were no signs of recent CMV infection in the mother, only anti-CMV IgG. The relationship between CMV infection and glomerular disease is still unclear; NS may represent another manifestation of CMV disease.