Minimally invasive assessment of the adequacy of perfusion of the gast
rointestinal tract has become clinically feasible with the availabilit
y of the gastric tonometer. This modified nasogastric tube permits cal
culation of the pH of the gut mucosal cells; a low tissue pH may indic
ate tissue hypoxia due to regional hypoperfusion. Such regional hypope
rfusion is often undetected by other monitors and, if it occurs intra-
operatively, may result in a poor outcome following major surgery. In
critical illness, the splanchnic area seems to be particularly vulnera
ble to hypoperfusion and such a regional oxygen deficit is implicated
in the causation of organ dysfunction/failure. Recent studies have beg
un to define the circumstances in which splanchnic tissue acidosis dev
elops and several therapies have been proposed to reverse the regional
oxygen deficit. This review seeks to clarify whether or not the tonom
eter is a valuable addition to our current monitoring aids.