Background. An excess of non-right-handedness has been shown among pat
ients with schizophrenia. However it is not clear whether this finding
can be accounted for by an increase in left-handedness, mixed-handedn
ess or both. It is not known whether atypical patterns of hand prefere
nces occur in other functional psychotic illnesses. Method. The Annett
hand preference questionnaire was administered to patients with schiz
ophrenia (n=120); affective psychosis (n=55); schizoaffective psychosi
s (n=41), and control subjects (n=86). Handedness was classified into
three categories: right, mixed and left-handedness. Results. The hand
preference patterns of patients with functional psychotic illnesses we
re not significantly different from controls. Patients with schizophre
nia showed a non-significant excess of mixed-handedness compared with
controls. Patients with schizophrenia and affective psychosis showed a
non-significant decrease in left-handedness compared with controls. C
onclusions. Although our results showed a trend in the hypothesised di
rection, we failed to demonstrate that patients with psychotic illness
differed from controls on self-reported hand preference patterns.