M. Medarde et al., CONJUGATE ADDITION OF 2-HETEROARYL-1,3-DITHIANES TO FURAN-2(5H)-ONE, Journal of the Chemical Society. Perkin transactions. I, (1), 1994, pp. 45-47
Conjugate addition of lithiated 2-heteroaryl-1,3-dithianes to furan-2(
5H)-one has been successfully achieved. This reaction proceeds with hi
gher yields than the addition of the 2-aryl derivatives, although it f
ails if the heteroaryl ring has strong deactivating substituents.