PROTOBERBERINES FROM REISSERT-COMPOUNDS . 5. SYNTHESIS OF (+ -)-BHARATAMINE/

Authors
REIMANN E RENZ H DAMMERTZ W SCHOLZ T
Citation
E. Reimann et al., PROTOBERBERINES FROM REISSERT-COMPOUNDS . 5. SYNTHESIS OF (+ -)-BHARATAMINE/, Monatshefte fuer Chemie, 127(2), 1996, pp. 173-176
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
127
Issue
2
Year of publication
1996
Pages
173 - 176
Database
ISI
SICI code
0026-9247(1996)127:2<173:PFR.5S>2.0.ZU;2-5
Abstract
Alkylation of the Reissert compound 1 by methyl 2-bromomethylbenzoate (2) followed by spontaneous intramolecular cyclization affords dibenzo [a, g]quinolizinone 4 which in turn can be reduced to benzyl ether 5 b y LiAlH4/NaBH4. Debenzylation of 5 by ethanolic HCl furnishes the titl e compound 6 in improved total yield.