SYNTHESIS OF A NOVEL TETRAPYRROLIC MACROLACTAM AND ITS ACTIVITY TOWARDS UROGEN-III SYNTHASE

Authors
PICHON C SCOTT AI
Citation
C. Pichon et Ai. Scott, SYNTHESIS OF A NOVEL TETRAPYRROLIC MACROLACTAM AND ITS ACTIVITY TOWARDS UROGEN-III SYNTHASE, Recueil des travaux chimiques des Pays-Bas, 115(1), 1996, pp. 1
Citations number
32
Categorie Soggetti
Chemistry
Journal title
Recueil des travaux chimiques des Pays-Bas → ACNP
ISSN journal
01650513
Volume
115
Issue
1
Year of publication
1996
Database
ISI
SICI code
0165-0513(1996)115:1<1:SOANTM>2.0.ZU;2-L
Abstract
A novel macrocyclic tetrapyrrolelactam 8, analog of a putative interme diate, has been synthesized. Its very low inhibitory effect on Uro'gen III synthase renders it unlikely to be a low-energy transition-state analog.