Hf. Clemo et al., ATRIAL-NATRIURETIC-PEPTIDE AND CARDIAC ELECTROPHYSIOLOGY - AUTONOMIC AND DIRECT EFFECTS, Journal of cardiovascular electrophysiology, 7(2), 1996, pp. 149-162
Atrial natriuretic peptide (ANP) has varied effects on cardiac electro
physiologic parameters including heart rate, intraatrial conduction ti
me, and refractory period, ANP's vagoexcitatory and sympathoinhibitory
actions as well as its direct actions on cardiac ion currents may be
responsible for some of these effects, This review discusses the role
of ANP in cardiac electrophysiology, its interactions with the autonom
ic nervous system and baroreceptor reflex, and its effects an cardiac
ion currents.