Jr. Carapetis et al., ACUTE RHEUMATIC-FEVER AND RHEUMATIC HEART-DISEASE IN THE TOP END OF AUSTRALIA NORTHERN-TERRITORY, Medical journal of Australia, 164(3), 1996, pp. 146-149
Objective: To describe the epidemiological and clinical features of ac
ute rheumatic fever and rheumatic heart disease in the Top End of the
Northern Territory. Methods: A retrospective review (in some instances
as far back as the 1960s) of all cases of known or suspected acute rh
eumatic fever or rheumatic heart disease, with prospective validation
of clinical status where necessary. Cases were ascertained from hospit
al and community medical clinic records and medical staff; and from re
cords and health staff of 10 rural communities. Results: Three hundred
and eighty-six revised Jones criteria-confirmed episodes of acute rhe
umatic fever were documented in 249 individuals (99% Aboriginal). The
annual incidence of confirmed acute rheumatic fever between 1989 and 1
993 was 254 per 100 000 Aboriginal people aged 5 to 14 years. A more a
ccurate estimate of 651 per 100 000 came from 10 rural communities wit
h more complete information. As of 1995, there were 286 people living
with established rheumatic heart disease (95% Aboriginal). The point p
revalence of rheumatic heart disease among Aboriginal people was 9.6 p
er 1000, with a rate of 24 per 1000 in one large rural community. Syde
nham's chorea was common, and associated with later rheumatic heart di
sease in 49% of cases. There was a preponderance of females with acute
rheumatic fever, rheumatic heart disease and chorea. Conclusions: In
Aboriginal people in rural northern Australia the incidence of acute r
heumatic fever is higher than that reported anywhere in the world, and
the prevalence of rheumatic heart disease is among the highest in the
world. While continuing attention must be paid to alleviating the cau
ses of these diseases of poverty, immediate action is needed to improv
e diagnosis of acute rheumatic fever, adherence to secondary benzathin
e penicillin prophylaxis regimens, and follow-up of rheumatic heart di
sease cases.