IMAGING OF OLFACTORY NEUROBLASTOMA BY IN-111 BLEOMYCIN COMPLEX

No other successful nuclear method, besides bone scanning, has been re ported in the literature for in vivo imaging of olfactory neuroblastom a. In this article, excellent uptake is reported by an In-111 labeled bleomycin complex (BLMC) in the ethmoid region of a histologically con firmed olfactory neuroblastoma. The uptake of BLMC was 0.7 x 10(-3)% I D/g at 48 hours after injection, and tumor-to-muscle and tumor-to-fat ratios were 6:1 and 11:1, respectively. The authors conclude that BLMC should be considered as a useful imaging agent, and that BLMC has pot ential as a radiochemotherapeutic agent against an olfactory neuroblas toma.