AZITHROMYCIN IN GONORRHEA

The clinical applications of azithromycin in gonorrhoea, often complic ated by simultaneously acquired infection with Chlamydia trachomatis, are reviewed in this paper. Clinical trials from major centres in Euro pe are compared with a large, more recent US study. At the present tim e, azithromycin is recommended throughout the world as a useful antibi otic in the treatment of gonorrhoea. It has several advantages in that it can be given as single-dose therapy, it can be given where the cau sative pathogen of urethritis/cervicitis is uncertain, and it is often , therefore, most useful in acute therapy where there is no immediate microbiological back-up. All these considerations are reviewed in deta il.