RECOGNITION OF NUCLEIC ACID-FUROCOUMARIN CROSS-LINKS BY HUMAN ANTI-DNA AUTOANTIBODIES

Authors
ARIF Z ALAM K ALI A ALI R
Citation
Z. Arif et al., RECOGNITION OF NUCLEIC ACID-FUROCOUMARIN CROSS-LINKS BY HUMAN ANTI-DNA AUTOANTIBODIES, Medical science research, 24(1), 1996, pp. 61-62
Citations number
16
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Medical science research → ACNP
ISSN journal
02698951
Volume
24
Issue
1
Year of publication
1996
Pages
61 - 62
Database
ISI
SICI code
0269-8951(1996)24:1<61:RONACB>2.0.ZU;2-9
Abstract
Anti-DNA autoantibodies from human SLE sera were tested for binding to poly(dA-dT)-8-MOP and DNA-8-MOP crosslinks. The specific crosslink-au toantibody interaction was confirmed by competition assay employing af finity purified anti-DNA IgG. The order of recognition by human anti-D NA autoantibody in this study was native DNA> poly(dA-dT)-8-MOP>DNA-8- MOP>DNA-psoralen.