THE ROLE OF GLUTAMIC-ACID IN THE PATHOGENESIS OF STROKE AND THE DEVELOPMENT OF NEUROPROTECTIVE DRUGS

Authors
EVANS SM ADDAE JI
Citation
Sm. Evans et Ji. Addae, THE ROLE OF GLUTAMIC-ACID IN THE PATHOGENESIS OF STROKE AND THE DEVELOPMENT OF NEUROPROTECTIVE DRUGS, West Indian Medical Journal, 44(4), 1995, pp. 119-123
Citations number
35
Categorie Soggetti
Medicine, General & Internal
Journal title
West Indian Medical Journal → ACNP
ISSN journal
00433144
Volume
44
Issue
4
Year of publication
1995
Pages
119 - 123
Database
ISI
SICI code
0043-3144(1995)44:4<119:TROGIT>2.0.ZU;2-O
Abstract
The role of glutamic acid (glutamate) in the pathogenesis of stroke is now fairly well established. As a result, many drugs which act on glu tamate receptors are currently under investigation for their ability t o prevent the damage induced by glutamate under ischaemic conditions. The efficacy of these compounds in protecting central neurones from th e effects of stroke may be indicative of the importance of the role th at glutamate plays in this process.