PURPOSE: To determine whether prothrombin time (PT), partial thrombopl
astin time (PTT), and platelet count are useful predictors of postangi
ographic hematoma. MATERIALS AND METHODS: The authors prospectively st
udied 1,000 consecutive patients who underwent femoral arterial punctu
re for a diagnostic or therapeutic vascular procedure. Demographic and
procedural variables were recorded, including patient age and sex, hi
story of medications and bleeding, procedure type and length, catheter
size, and experience level of radiologist applying compression for he
mostasis. RESULTS: Abnormal results of coagulation tests were not corr
elated with an increased occurrence of hemorrhagic complications, but
bleeding complications did occur more often in patients with thrombocy
topenia. Hematomas occurred in 8.1% (10 of 123) of patients with any a
bnormal coagulation test results and 9.7% (85 of 877) of patients with
normal test results. A platelet count of less than 100 x 10(9)/L was
correlated with a higher occurrence of hematoma (P =.002).CONCLUSION:
Abnormal PTs and PTTs do not correlate with an increased risk of posta
ngiographic hematoma, but a low platelet count is associated with more
bleeding complications.