PURPOSE: To analyze difficult diagnostic cases of malrotation to ident
ify features crucial to accurate diagnosis. MATERIALS AND METHODS: The
authors reviewed the radiographs and records of 81 symptomatic childr
en who underwent surgery with a preoperative diagnosis of malrotation.
Eleven had subtle rotational abnormalities (potential false-negative
examinations), and 12 had false-positive upper gastrointestinal examin
ations. RESULTS: Subtle signs of malrotation included unusual redundan
cy of the duodenum to the right of the spine and location of the duode
nojejunal junction (DJJ) medial to the left pedicle. Nevertheless, two
children with variations of malrotation had normal upper gastrointest
inal examinations. False-positive diagnoses resulted from failure to r
ecognize normal variants: jejunum in the right upper quadrant as the s
ole finding, DJJ over the left pedicle on the anteroposterior view, ''
duodenum inversum,'' and ''duodenum mobile.'' Three children had bowel
distention that displaced the DJJ. CONCLUSION: Diagnosis of difficult
cases of malrotation may depend on recognition of anatomic subtleties
. False-positive diagnoses may be avoided by appreciation of normal du
odenal variants.