Background: Advance directives are intended to extend patient autonomy
into periods of mental incompetence. However, for advance directives
to fulfill this objective, patients' choices must be reasonably consis
tent over time. Thus, we assessed the stability of the advance treatme
nt decisions of patients and members of the public. Methods: In a pros
pective cohort study of 495 outpatients and 102 members of the public,
we studied the stability of scenarios and treatment-specific choices.
Subjects completed an advance directive, which included four illness
scenarios with 11 treatment choices in each, as part of a questionnair
e. A second interview was completed by 296 patients and 78 members of
the public after 6 to 12 months; 154 patients completed a third interv
iew after a further 6 to 12 months. We assessed stability by comparing
each choice between interviews. Results: Stability of choices was mod
erately high among patients (pooled K=0.39) and members of the public
(pooled K=0.48). Stability improved with repeat interview (pooled K=0.
47 among patients). Patients who had discussions with their physicians
showed more improvement (K=0.57) than others. Patients had a wide ran
ge of personal stability levels (O% to 100%), but individuals starting
out stable rarely became less so (93% of the patients with 85% to 100
% stability maintained this level of stability on the third interview)
. Hospitalized patients showed no significant difference in stability
at the second interview, but their stability was not improved at the t
hird interview. Conclusions: Our findings generally support the use of
advance directives. Most people made moderately stable decisions when
using scenario- and treatment-specific directives, and stability impr
oved after they reviewed the decisions, especially among those who had
discussions with their physicians. Recent hospitalization did not dec
rease stability, although it appeared to reduce the improvement that o
thers achieved with repeat interview. These findings suggest that adva
nce directives can be relied on 1 to 2 years after completion to refle
ct a patient's choices.