Mg. Gonzalez et Om. Matamoros, CARDIOVASCULAR EFFECTS OF LEAF WATER EXTR ACT IN CLUSIA-COCLENSIS (GUTTIFERAE), Revista de biologia tropical, 44(1), 1996, pp. 87-91
Aqueous extracts of the leaves of Clusia coclensis, (Guttiferae) injec
ted intravenously to 42 normal Sprague-Dawley rats and to 42 Spontaneo
us Hypertensive rats, in 7 different doses, induced a rapid and transi
tory decrease in blood pressure and heart frequency. The magnitude of
blood pressure decrease was dose-dependent. The effect was statistical
ly significant (p less than or equal to 0.01), probably due to sympath
etic stimuli.