N. Jobspira et al., FERTILITY AFTER ECTOPIC PREGNANCY - FIRST RESULTS OF A POPULATION-BASED COHORT STUDY IN FRANCE, Human reproduction, 11(1), 1996, pp. 99-104
The purpose of this paper was to evaluate the reproductive outcome aft
er ectopic pregnancy (EP) from a population-based register in the cent
re of France. Since 1992, all the women aged 15-44 years, who permanen
tly reside in the target area and who were treated either by surgical
or medical procedures for an ectopic pregnancy in one of the area cent
res, have been registered and prospectively followed until 45 years of
age, The analysis presented was based on the 155 women registered bet
ween January 1992 and March 1994 who were followed up for at least 6 m
onths, and who were seeking a new pregnancy, The mean follow-up period
was 16 months. A total of 102 women (66%) obtained a pregnancy. The f
irst conception was intrauterine for 92 women, and 10 had a recurrence
of ectopic pregnancy, Risk factors of recurrence were prior spontaneo
us abortion and prior tubal damage, For those women who conceived, the
mean time to obtain pregnancy ('time to pregnancy') was 4.8 months, T
he 1 year cumulative intrauterine pregnancy rate (i.e. the probability
of obtaining an intrauterine pregnancy within 1 year of seeking pregn
ancy) was 70%, After multivariate analysis by a Cox regression, the fa
ctors associated with higher fertility were age < 30 years, high educa
tional level and no prior tubal damage.