Aim. To identify trends in the prescribing of antihypertensive medicat
ions and measure the changes in government and patient expenditure res
ulting from any identified change. Methods. The computerised records o
f 16 069 patients from six Otago practices from 1991-3 were examined.
Those patients prescribed any antihypertensive medication in all 3 yea
rs were selected for investigation. The antihypertensives prescribed w
ere assigned to one of seven classes. The cohort was then divided into
two groups; those remaining on the same class of medication for the t
hree years and those changing medication class at any stage. Reasons f
or any change were identified. The direct costs of the prescribing dec
isions taken were evaluated. Results. 914 patients were prescribed ant
ihypertensives in all 3 years. Of these 579 (63.3%) remained on the sa
me class of medication, while 335 (36.7%) changed class. A clinical re
ason was identified for medication change in 98% of cases available fo
r examination. There was no significant shift in expenditure for those
remaining on the same medication, while costs increased by 20.6% for
those changing. Conclusion. For this cohort increased expenditure on a
ntihypertensives was driven by those changing medication. Although the
se changes were prompted by clinical reasons, better health outcomes f
or patients cannot be assumed due to lack of objective indicators.