In situ and in vivo treatment plan verification and beam monitoring as
well as dose control during heavy-ion tumour therapy can be performed
in principle by measurements of range distributions of beta(+)-emitti
ng nuclei by means of PET techniques. For this purpose the performance
of different types of positron camera as well as the results of in-be
am PET experiments using beams of beta(+)-active heavy ions (O-15, F-1
7 and Ne-19 with energies of 300-500 A MeV) are presented. Following t
he deduced performance requirements a PET scanner that is designed for
clinical use in experimental heavy-ion therapy at GSI Darmstadt has b
een built. This limited angle tomograph consists of two large-area det
ector heads based on position sensitive EGO detectors and is predicted
to perform the measurement of the end point of a beta(+)-emitting ion
beam for the verification of a treatment plan with a precision better
than 1 mm. The maximum dose applied in the patient thereby is of the
magnitude of 10 mGy.