THE INVESTIGATION OF DIFFERENT CAMERAS FOR IN-BEAM PET IMAGING

Citation
J. Pawelke et al., THE INVESTIGATION OF DIFFERENT CAMERAS FOR IN-BEAM PET IMAGING, Physics in medicine and biology, 41(2), 1996, pp. 279-296
Citations number
25
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
00319155
Volume
41
Issue
2
Year of publication
1996
Pages
279 - 296
Database
ISI
SICI code
0031-9155(1996)41:2<279:TIODCF>2.0.ZU;2-2
Abstract
In situ and in vivo treatment plan verification and beam monitoring as well as dose control during heavy-ion tumour therapy can be performed in principle by measurements of range distributions of beta(+)-emitti ng nuclei by means of PET techniques. For this purpose the performance of different types of positron camera as well as the results of in-be am PET experiments using beams of beta(+)-active heavy ions (O-15, F-1 7 and Ne-19 with energies of 300-500 A MeV) are presented. Following t he deduced performance requirements a PET scanner that is designed for clinical use in experimental heavy-ion therapy at GSI Darmstadt has b een built. This limited angle tomograph consists of two large-area det ector heads based on position sensitive EGO detectors and is predicted to perform the measurement of the end point of a beta(+)-emitting ion beam for the verification of a treatment plan with a precision better than 1 mm. The maximum dose applied in the patient thereby is of the magnitude of 10 mGy.