For diagnosis of pulmonary embolism (PE), ventilation/perfusion lung s
cintigraphy is routinely used; approximately one-third of the patients
will have the diagnosis ''intermediate probability of PE'' (inconclus
ive). In this group only about 33% are found to have pulmonary emboli
if examined with pulmonary angiography. To evaluate the diagnostic, th
erapeutic, and economic consequences of ultrasound of the legs as a co
mplementary diagnostic investigation to ''intermediate probability'',
72 consecutive patients were investigated with bilateral ultrasound of
the proximal deep veins of the legs and pulmonary angiography in a pr
ospective study. Ten patients had PE, of whom 7 had deep venous thromb
osis, and 62 had no PE, of whom 2 had deep venous thrombosis. The nega
tive predictive value of ultrasound was 0.95. In view of the importanc
e of adequate treatment and rational use of public health care expendi
ture. complementary diagnostics should be performed. and ultrasound is
an adequate complementary investigation.