CLONING OF A PUTATIVE GAMMA-AMINOBUTYRIC-ACID (GABA) RECEPTOR SUBUNITRHO3 CDNA

Citation
T. Ogurusu et R. Shingai, CLONING OF A PUTATIVE GAMMA-AMINOBUTYRIC-ACID (GABA) RECEPTOR SUBUNITRHO3 CDNA, Biochimica et biophysica acta, N. Gene structure and expression, 1305(1-2), 1996, pp. 15-18
Citations number
16
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
ISSN journal
01674781
Volume
1305
Issue
1-2
Year of publication
1996
Pages
15 - 18
Database
ISI
SICI code
0167-4781(1996)1305:1-2<15:COAPG(>2.0.ZU;2-T
Abstract
Cloned cDNA encoding a putative member of GABA receptor rho-subunit cl ass was isolated from rat-retina-mRNA-derived libraries. The cDNA enco des a signal peptide of 21 amino acids followed by the mature rho 3 su bunit sequence of 443 amino acids. The proposed amino acid sequence ex hibits 63 and 61% homology to the previously-reported human rho 1 and rat rho 2 sequences, respectively. Northern blot analysis demonstrated the expression of mRNA for rho 3 subunit in retina.