T. Ogurusu et R. Shingai, CLONING OF A PUTATIVE GAMMA-AMINOBUTYRIC-ACID (GABA) RECEPTOR SUBUNITRHO3 CDNA, Biochimica et biophysica acta, N. Gene structure and expression, 1305(1-2), 1996, pp. 15-18
Cloned cDNA encoding a putative member of GABA receptor rho-subunit cl
ass was isolated from rat-retina-mRNA-derived libraries. The cDNA enco
des a signal peptide of 21 amino acids followed by the mature rho 3 su
bunit sequence of 443 amino acids. The proposed amino acid sequence ex
hibits 63 and 61% homology to the previously-reported human rho 1 and
rat rho 2 sequences, respectively. Northern blot analysis demonstrated
the expression of mRNA for rho 3 subunit in retina.