Ne. Sharrock et Ea. Salvati, HYPOTENSIVE EPIDURAL-ANESTHESIA FOR TOTAL HIP-ARTHROPLASTY - A REVIEW, Acta orthopaedica Scandinavica, 67(1), 1996, pp. 91-107
Hypotensive epidural anesthesia provides arterial hypotension to maint
ain a mean arterial pressure of 50 mmHg and it can be used to reduce b
lood loss during total hip replacement. The technique combines an exte
nsive epidural blockade with an intravenous infusion of low-dose epine
phrine. This results in arterial hypotension, but with preservation of
central venous pressure, heart rate, stroke volume, cardiac output, a
nd an augmentation of blood Row to the lower extremity. The technique
does not appear to adversely affect cardiac, renal, or cerebral functi
on and is used safely in patients with hypertension, ischemic heart di
sease, and in the elderly. Intraoperative blood losses during primary
total hip replacement are between 100 and 300 mt. Perioperative transf
usions have declined with the introduction of the technique. Radiologi
cal evidence of improved fixation of cemented acetabular components ha
s been observed. Rates of deep-vein thrombosis are low: 2-3% proximal
deep-vein thrombosis with an overall rate of 10%. In-hospital mortalit
y is 0.1%; lower than previously published rates. In conclusion, hypot
ensive epidural anesthesia is safe and provides a number of advantages
over conventional anesthetic techniques for total hip replacement.