UNEXPECTED ALKYLATION REACTION OF AMINES, ACIDS AND PHENOLS BY ALKYL (TRIPHENYLPHOSPHORANYLIDENE)ACETATES

Authors
DESMAELE D
Citation
D. Desmaele, UNEXPECTED ALKYLATION REACTION OF AMINES, ACIDS AND PHENOLS BY ALKYL (TRIPHENYLPHOSPHORANYLIDENE)ACETATES, Tetrahedron letters, 37(8), 1996, pp. 1233-1236
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
8
Year of publication
1996
Pages
1233 - 1236
Database
ISI
SICI code
0040-4039(1996)37:8<1233:UAROAA>2.0.ZU;2-4
Abstract
Reaction of methyl (triphenylphosphoranylidene)acetate in methanol wit h primary and secondary amines led to N-methylated derivatives. Simila rly this mixture reacted with acids, phenol and phthalimide to afford methyl esters, anisole and N-methylphthalimide respectively. Treatment of ketolactam 2 by this mixture water high pressure activation gave t he rearranged quinolinone 5.