ACYCLIC 1,2- 1,3-MIXED PENTOLS - SYNTHESIS AND GENERAL TRENDS IN BICHROMOPHORIC EXCITON COUPLED CIRCULAR DICHROIC SPECTRA/

The synthesis of all eight configurational isomers of acyclic 1,2,3,4, 6-pentols belonging to the 2R enantiomeric series is described. The 1- anthroyl-2,3,4,6-p-methoxycinnamates of these pentols give rise to uni que exciton coupled circular dichroic spectra in the range of 220-380 nm. Comparisons with the CD of corresponding bichromophoric derivative s of the lower homologous tetrols, 1-anthroyl-2,3,4-p-methoxycinnamate s led to a predictable general trend in which only minor differences r esult from 1,3-syn extensions whereas major differences result from 1, 3-anti extensions.