In this case we evaluated brain tissue pO(2), pCO(2) and pH during isc
hemia and arterial oxygen desaturation (hypoxia). In both situations b
rain pO(2) decreased. During ischemia, tissue pCO(2) increased while p
H decreased; but both pCO(2) and pH were stable during hypoxia. These
results suggest that brain tissue pO(2), pCO(2) and pH measures provid
e information on tissue perfusion and oxygen availability during ische
mia and hypoxia.