Paroxysmal atrial flutter is a drug-resistant supraventricular tachyar
rhythmia that is often accompanied by hemodynamic instability due to a
n excessive ventricular response. We report here a case of atrial flut
ter with 1:1 atrioventricular conduction, in which we were able to res
cue the patient from a state of cardiogenic shock by using intravenous
dofetilide, a new class III antiarrhythmic agent. Dofetilide was suit
able for the treatment because it immediately increased atrioventricul
ar nodal refractoriness without any negative inotropic action.