ACQUIRED MULTIFOCAL MYOFIBRILLAR DISRUPTION SELECTIVE OF TYPE-II FIBERS

We report three cases of patients who complained of myalgia showing hi stological features similar to tubular aggregates in their muscle biop sies, All had an elevated erythrocyte sedimentation rate without any e vidence of infectious or autoimmune disease. On electron microscopy, s mall areas of myofibrillar degeneration, selectively in type II fibres , were found in all patients, but no tubular aggregates were seen. Alt hough the pathogenesis of these lesions is unclear, it does seem that this condition is acquired and transient.