Resurgence of Kala-Azar in India has posed many problems. Apart from p
atients from endemic areas, cases are being reported from non-endemic
areas also. In the present series, four out of 26 patients were from n
on-endemic areas. Other than diagnostic difficulties, resistance to st
ibogluconate and relapse are common problems which were seen in eight
patients. The clinical profile of cases, their management, and how the
problem of resistance was tackled are described.