AUTONOMIC CHARACTERISTICS OF GENERALIZED ANXIETY DISORDER AND WORRY

Citation
Jf. Thayer et al., AUTONOMIC CHARACTERISTICS OF GENERALIZED ANXIETY DISORDER AND WORRY, Biological psychiatry, 39(4), 1996, pp. 255-266
Citations number
118
Categorie Soggetti
Psychiatry
Journal title
ISSN journal
00063223
Volume
39
Issue
4
Year of publication
1996
Pages
255 - 266
Database
ISI
SICI code
0006-3223(1996)39:4<255:ACOGAD>2.0.ZU;2-K
Abstract
Autonomic characteristics of generalized anxiety disorder (GAD) and wo rry were examined using measures of heart period variability. The card iorespiratory responses of 34 GAD clients and 32 nonanxious control su bjects were recorded during resting baseline, relaxation, and worry pe riods. Results indicated differences between GAD subjects and controls as well as among baseline, relaxation, and worry periods. GAD clients exhibited shorter cardiac interbeat intervals (IBIs) and lower high f requency spectral power across all task conditions. Relative to baseli ne and relaxation conditions, worry, was associated with (I) shorter I BIs, (2) smaller mean successive differences (MSD) of the cardiac IBIs , and (3) lower high frequency spectral power. These findings suggest that GAD and its cardinal feature (worry), are associated with lower c ardiac vagal control. The findings of the present study provide eviden ce for the utility of further exploration of the role of autonomic ner vous system activity in GAD.