In this paper we present investigations on a simplified method of quan
titative whole body scintigraphy by using a dual head LFOV-gamma camer
a and a calibration algorithm without the need of additional attenuati
on or scatter correction. Validation of this approach to the anthropom
orphic phantom as well as in patient studies showed a high accuracy co
ncerning quantification of whole body activity (102.8% and 97.72%, res
p.), by contrast organ activities were recovered with an error range u
p to 12%. The described method can be easily performed using commercia
lly available software packages and is recommendable especially for qu
antitative whole body scintigraphy in a clinical setting.