NONEXPONENTIAL LIGAND REBINDING OF CO AND O-2 IN MYOGLOBIN CONTROLLEDBY FLUCTUATIONS OF THE PROTEIN

The kinetics of first-order processes which depend on a fluctuating co ordinate are studied analytically. The fluctuations are described as u ncorrelated jumps with an arbitrary time distribution between jumps. A s an example, the nonexponential ligand rebinding kinetics in proteins is analyzed in the adiabatic limit where the reaction is controlled b y the motion along the reaction coordinate. A new powertime law is ded uced for the rebinding at low temperatures.