NEW ASPECTS OF CYTOSOLIC CALCIUM SIGNALING

Authors
PETERSEN OH
Citation
Oh. Petersen, NEW ASPECTS OF CYTOSOLIC CALCIUM SIGNALING, News in physiological sciences, 11, 1996, pp. 13-17
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
11
Year of publication
1996
Pages
13 - 17
Database
ISI
SICI code
0886-1714(1996)11:<13:NAOCCS>2.0.ZU;2-I
Abstract
Hormone- or neurotransmitter-evoked cytosolic Ca2+ signals are general ly thought to be initiated by an increase in inositol trisphosphate (I P3) concentration that in turn opens Ca2+ release channels in the endo plasmic reticulum. Recent data challenge this simple model and indicat e IP3 receptors in several organelles and an additional intracellular messenger system for Ca2+ regulation.