THE EFFECT OF SALINOMYCIN AND LASALOCID ON LABORATORY CULTURES OF ENTEROCOCCUS-FAECIUM AND STAPHYLOCOCCUS-GALLINARUM STRAINS

The growth of Enterococcus faecium strains CCM 4231 and EF 26, and Sta phylococcus gallinarum SG 31 was inhibited by salinomycin and lasaloci d at concentrations of 25 and 50 mg/L. Staphylococcus gallinarum was m ore sensitive to the additives used than were enterococci. Maximum inh ibition (90 %) was measured after the growth with the SG 31 strain in the presence of both ionophores. Growth of organisms was more inhibite d by salinomycin at 25 mg/L (67.5 %) than at 50 mg/L (63 %). The inhib itory effect in enterococcal strains reached after the addition of sal inomycin and lasalocid (on average) 63 and 58 %, respectively. The CCM 4231 strain was more inhibited by salinomycin as well as by lasalocid than was the EF 26 strain.