A SHORT SYNTHESIS OF 4-(3-FURYL)-4-OXOBUTANOIC ACID AND SYNTHESIS OF EGOMAKETONE

Authors
KOYANAGI J YAMAMATO K NAKAYAMA K TANAKA A
Citation
J. Koyanagi et al., A SHORT SYNTHESIS OF 4-(3-FURYL)-4-OXOBUTANOIC ACID AND SYNTHESIS OF EGOMAKETONE, Journal of natural products, 58(12), 1995, pp. 1955-1957
Citations number
15
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
58
Issue
12
Year of publication
1995
Pages
1955 - 1957
Database
ISI
SICI code
0163-3864(1995)58:12<1955:ASSO4A>2.0.ZU;2-Y
Abstract
3-Lithiofuran THF was added to succinic anhydride in THF to yield 4-(3 -furyl)-4-oxobutanoic acid [1]. Egomaketone [2], isolated from Perilla frutescens was synthesized from 1 in lour steps. The isomer of 2, 5-( 3-furyl)-2-methyl-5-oxo-1-pentene [6], was also prepared from 1.