Background. Early experience in other centers with pediatric assist de
vices has been favorable. Methods. Prospectively we examined our first
13 patients between January 1992 and September 1994. Results. Thirtee
n children underwent ventricular assistance at Royal Alexandra Hospita
l for Children. Age ranged from 4 days to 30 months, weight from 2.9 k
g to 17 kg. Ventricular assistance was employed from 1.5 hours to 190
hours. Of 12 surgical patients, 8 required left ventricular assistance
to be weaned from cardiopulmonary bypass after correction of congenit
al defects, and 4 required support in the postoperative period for ref
ractory low cardiac output. A child was supported after a kick to the
chest by a horse caused cardiogenic shock. All 13 patients initially r
esponded to ventricular assistance and 7 remain alive. Of the deaths,
2 were neurologic, 2 due to myocardial failure, and 2 to sepsis. The m
ajor complications in the first days were hemorrhage and tamponade. La
ter problems included thrombosis of the circuit despite systemic hepar
inization, and a cannula-related tear to the anterior mitral leaflet.
The 7 survivors are well after 3 to 32 months. Conclusions. Despite th
e mortality and complications, we are encouraged by these results, in
the light of almost certain death for all 13 patients without ventricu
lar assistance.