EFFECT OF REM-SLEEP DEPRIVATION ON SLEEP APNEAS IN RATS

We studied the effects of 48 h of REM sleep deprivation on spontaneous and post-sigh central apneas in Sprague-Dawley rats by simultaneously monitoring sleep by the EEG and respiration for 6 h. During the recov ery sleep following REM deprivation a decrease in post-sigh apneas occ urred in total sleep. There was no change in spontaneous apneas. The r esults suggest the existence of partially distinct mechanisms for the two types of apneas. (C) 1996 Academic Press, Inc.