NEW HYPOGLYCEMIC CONSTITUENTS IN GYMNEMIC ACID FROM GYMNEMA-SYLVESTRE

Authors
MURAKAMI N MURAKAMI T KADOYA M MATSUDA H YAMAHARA J YOSHIKAWA M
Citation
N. Murakami et al., NEW HYPOGLYCEMIC CONSTITUENTS IN GYMNEMIC ACID FROM GYMNEMA-SYLVESTRE, Chemical and Pharmaceutical Bulletin, 44(2), 1996, pp. 469-471
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
44
Issue
2
Year of publication
1996
Pages
469 - 471
Database
ISI
SICI code
0009-2363(1996)44:2<469:NHCIGA>2.0.ZU;2-E
Abstract
Investigation of hypoglycemic activity of major saponin constituents f rom ''gymnemic acid'', a crude saponin fraction of G. sylvestre, expos ed not only two new saponins, gymnemosides a (1) and b (2), but also g ymnemoside b and gymnemic acid V (7) as active principles. Furthermore , an acetyl group linked 16- or 22-hydroxy group in 1 and 2 was found to migrate easily to primary 28-hydroxyl group, while acyl migration f rom 28-hydroxy group in 3 was little observed.