Peritonitis-induced stress triggers a very sophisticated humoral and m
etabolic reaction. Inflammatory, immunological and vasoactive pathways
act to control infection. In many cases, this response outbreaks the
goal and induces multiple organ failure. Energetic and protein stores
are overlaped. Then nutritional support is one of the way by which out
come may improve. Some nutrients have pharmacological properties which
can modulate response to stress. This new therapeutic prospect includ
es new lipid substrates (fish oil, structured lipids, medium-chain tri
glycerides), amino acids (glutamine, arginine) and free radical scaven
gers (vitamines, trace elements or enzyme-dependant). Enteral nutritio
n is probably the best way for nutritional support in this disease.