The surgical management of secondary peritonitis is based on the follo
wing principles : control of the pathologic process causing the bacter
ial contamination, peritoneal toilet and prevention of recurrent infec
tion. Gastric and small bowel perforations are generally treated by si
mple suture or resection with primary anastomosis. Peritonitis seconda
ry to large bowel perforation results in 15 to 60% mortality depending
on the etiology of the perforation. Some studies have questioned the
surgical dogma which forbids primary anastomosis after perforated sigm
oid diverticulitis or traumatic colonic perforation. The interest for
laparoscopy in peritonitis is based on the theorical advantage of redu
cing the morbidity of midline incisions of the contaminated abdomen. L
aparoscopy seems to be admitted as treatment for biliary peritonitis (
acute cholecystitis). The indication for laparoscopic treatment of app
endicular peritonitis or duodenal ulcer perforation however has still
to be validated. Peroperative peritoneal lavage with isotonic solution
s, with or without antiseptics or antibiotics, as well as the systemat
ic and complete peritoneal debridment have not shown any advantage in
terms of reduction of intra peritoneal abscesses or reduction of morta
lity. In advanced peritonitis, the utility of postoperative peritoneal
lavage, planned relaparotomies as well as laparostomy has yet to be e
stablished. Future prospective evaluations of surgical techniques for
the treatment of secondary peritonitis should include a severity score
, preferably based on the preoperative APACHE II score, rather than on
peroperative findings.