CONGENITAL MULLERIAN ANOMALIES - DIAGNOSTIC-ACCURACY OF 3-DIMENSIONALULTRASOUND

Objective: To determine whether it is possible to identify and diagnos e accurately Mullerian anomalies with three-dimensional (3-D) ultrasou nd (US). Design: Controlled blinded clinical study. Setting: Normal hu man volunteers undergoing infertility evaluation in a university hospi tal. Patients: Forty-two patients who underwent laparoscopy and hyster osalpingography as:part of their work up for infertility and were foun d to have either a normal uterus (30 patients) or a Mullerian abnormal ity (12 patients) consented to be evaluated with 3-D US by sonographer s who were unaware of their infertility history or of their laparoscop y and hysterosalpingography diagnoses. Interventions: Transvaginal 3-D US evaluation over a 10- to 15-minute duration. Main Outcome Measures : Three-dimensional imaging was successful in all cases. Results: Sono graphers identified a Miillerian anomaly in all cases and came up with the correct classification in 11 of 12 cases. AU patients with a norm al uterus were identified correctly. Conclusions: In all patients with Mullerian anomalies, 3-D US examination of the endometrial cavity cor related with hysterosalpingography. In 91.6% of patients, 3-D US corre lated with the external uterine configuration observed by :laparoscopy . This technique may be used reliably in an office setting to diagnose and classify Mullerian anomalies.