DIFFERENT CARDIAC MYOSIN ISOFORMS EXHIBIT EQUAL FORCE-GENERATING ABILITY IN-VITRO

Authors
SUGIURA S KOBAYAKAWA N MOMOMURA S CHAEN S OMATA M SUGI H
Citation
S. Sugiura et al., DIFFERENT CARDIAC MYOSIN ISOFORMS EXHIBIT EQUAL FORCE-GENERATING ABILITY IN-VITRO, Biochimica et biophysica acta. Bioenergetics, 1273(2), 1996, pp. 73-76
Citations number
24
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Bioenergetics → ACNP
ISSN journal
00052728
Volume
1273
Issue
2
Year of publication
1996
Pages
73 - 76
Database
ISI
SICI code
0005-2728(1996)1273:2<73:DCMIEE>2.0.ZU;2-Q
Abstract
We measured forces generated by myosin molecules and a single actin fi lament using an optical trap system. The force per unit length of acti n filament did not differ significantly between cardiac myosin isoform s, V-1 and V-3. This indicates that the ability to generate force is e qual between V-1 and V-3, despite their difference in the unloaded sli ding velocity past actin.