FLUORINATION OF 5'-DEOXY-5'-(METHYLTHIO)ADENOSINE WITH XENON DIFLUORIDE PROVIDES AN EXPEDIENT SYNTHESIS OF (FLUOROMETHYLTHIO)ADENOSINE

Citation
G. Guillerm et M. Gatel, FLUORINATION OF 5'-DEOXY-5'-(METHYLTHIO)ADENOSINE WITH XENON DIFLUORIDE PROVIDES AN EXPEDIENT SYNTHESIS OF (FLUOROMETHYLTHIO)ADENOSINE, Journal of the Chemical Society. Perkin transactions. I, (2), 1994, pp. 153-154
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
0300922X
Issue
2
Year of publication
1994
Pages
153 - 154
Database
ISI
SICI code
0300-922X(1994):2<153:FO5WXD>2.0.ZU;2-S
Abstract
Fluorination of 5'-deoxy-5'-(fluoromethylthio)adenosine derivatives wi th xenon difluoride at -60 degrees C in dichloromethane occurs exclusi vely at the methylthio position to provide a simple and efficient prep aration of 5'-deoxy-5'-(fluoromethylthio)adenosine.