Retinoblastoma, though uncommon, frequently is associated with other s
econd malignant neoplasms, especially bone sarcomas, These second neop
lasms can occur in sporadic cases of retinoblastoma, though they more
commonly are associated with genetic forms of the disease, This is the
first known report of 2 histologically distinct bone sarcomas in a pa
tient with retinoblastoma.