DETERMINATION OF POLYETHYLENE GLYCOLS IN WATER BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Authors
MOLDOVAN Z LUQUE MVD SALAVERRI EO SUAREZ A ANDREOZZI R INSOLA A MARTINEZ JL
Citation
Z. Moldovan et al., DETERMINATION OF POLYETHYLENE GLYCOLS IN WATER BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Journal of chromatography, 723(2), 1996, pp. 243-249
Citations number
24
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography → ACNP
Volume
723
Issue
2
Year of publication
1996
Pages
243 - 249
Database
ISI
SICI code
Abstract
This paper describes an RP-HPLC method to characterize the ozonation p roducts of polyethylene glycols (PEGs) (general formula HO(CH2CH2O)(n) -H) with original mass 5000. Samples with different pH and ozonation t imes were studied. The amounts of individual products up to n = 56, th e percentage of PEGs as a final product and the molecular distribution (M(w)/M(n)) were calculated. The samples were concentrated by liquid- liquid extraction.