STEREOSELECTIVE ENZYMATIC-HYDROLYSIS OF DIMETHYL MESO-PIPERIDINE-3,5-DICARBOXYLATES

Authors
DANIELI B LESMA G PASSARELLA D SILVANI A
Citation
B. Danieli et al., STEREOSELECTIVE ENZYMATIC-HYDROLYSIS OF DIMETHYL MESO-PIPERIDINE-3,5-DICARBOXYLATES, Tetrahedron : asymmetry, 7(2), 1996, pp. 345-348
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
2
Year of publication
1996
Pages
345 - 348
Database
ISI
SICI code
0957-4166(1996)7:2<345:SEODM>2.0.ZU;2-H
Abstract
Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c w ith pig liver esterase (PLE), lipase from Candida cylindracea (CCL) an d porcine pancreatic lipase (PPL) is described. The enantioselectiviti es of the enzymatic transformations and the absolute configurations of the resulting half-esters 2a-c were determined.