RHODIUM(I) BIS(AMINOPHOSPHANE) COMPLEXES AS CATALYSTS FOR ASYMMETRIC HYDROGENATION OF ACTIVATED KETONES

Authors
ROUCOUX A SUISSE I DEVOCELLE M CARPENTIER JF AGBOSSOU F MORTREUX A
Citation
A. Roucoux et al., RHODIUM(I) BIS(AMINOPHOSPHANE) COMPLEXES AS CATALYSTS FOR ASYMMETRIC HYDROGENATION OF ACTIVATED KETONES, Tetrahedron : asymmetry, 7(2), 1996, pp. 379-382
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
2
Year of publication
1996
Pages
379 - 382
Database
ISI
SICI code
0957-4166(1996)7:2<379:RBCACF>2.0.ZU;2-I
Abstract
The synthesis of new homochiral bis(aminophosphanes) (BAMP) 1-5 and th eir application in rhodium based asymmetric hydrogenation of dihydro-4 ,4-dimethyl-2,3-furandione 12 and N-benzylbenzoylformamide 14 are pres ented. Under mild conditions, the hydrogenations led to high enantiome ric excesses (up to 87% and 75% ee respectively for both substrates).