HIGHLY DIASTEREOSELECTIVE ADDITION OF METHYL 2-(N-BENZYLAMINO)-1-CYCLOHEXENECARBOXYLATE TO CHIRAL ACRYLATES

Authors
HERVOUET K GUINGANT A
Citation
K. Hervouet et A. Guingant, HIGHLY DIASTEREOSELECTIVE ADDITION OF METHYL 2-(N-BENZYLAMINO)-1-CYCLOHEXENECARBOXYLATE TO CHIRAL ACRYLATES, Tetrahedron : asymmetry, 7(2), 1996, pp. 425-426
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
2
Year of publication
1996
Pages
425 - 426
Database
ISI
SICI code
0957-4166(1996)7:2<425:HDAOM2>2.0.ZU;2-T
Abstract
Conjugate addition reaction of achiral Methyl 2-(N-benzylamino)-1-cycl ohexenecarboxylate 2 to chiral acrylates 4a, 4b, 4c led, after treatme nt of the primary adducts with sodium methoxyde, to alpha,alpha-disubs tituted beta-keto ester 1 with high enantiomeric excesses.