PENICILLAMINE - AN EXTRACTABLE CHIRAL AUXILIARY PROVIDING EXCELLENT STEREOCONTROL

Citation
Ls. Richter et Tr. Gadek, PENICILLAMINE - AN EXTRACTABLE CHIRAL AUXILIARY PROVIDING EXCELLENT STEREOCONTROL, Tetrahedron : asymmetry, 7(2), 1996, pp. 427-434
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
ISSN journal
09574166
Volume
7
Issue
2
Year of publication
1996
Pages
427 - 434
Database
ISI
SICI code
0957-4166(1996)7:2<427:P-AECA>2.0.ZU;2-3
Abstract
A synthetic route for racemization-free incorporation of derivatives o f penicillamine into the bislactim ether template is reported. Penicil lamine-derived bislactim ethers exhibit excellent stereodiscrimination , and the chiral auxiliary can be removed from the target amino acid e ster by simple extraction.